JAK Inhibitors · Autoimmune Diseases

Selective inhibition for immune-mediated disease.

Selective inhibition for immune-mediated disease.

Vyome’s preclinical JAK inhibitor franchise includes selective small-molecule assets designed to address cytokine-driven immune and inflammatory responses.

Vyome’s preclinical JAK inhibitor franchise includes selective small-molecule assets designed to address cytokine-driven immune and inflammatory responses.

Preclinical development · Programs advancing

Preclinical programs advancing

Scientist working in a laboratory

The autoimmune disease need

A targeted route through complex immune signaling.

Autoimmune diseases are often driven by dysregulated cytokine signaling. Current therapies can leave significant gaps in efficacy, selectivity, and tolerability.

Vyome’s JAK franchise is designed around selective pathway inhibition

Selective JAK 1/3 inhibitor asset for cytokine-driven inflammatory signaling

Selective JAK 1 inhibitor asset for targeted immune-pathway modulation

Preclinical program

Two selective assets advancing in the JAK pathway.

Two selective assets advancing in the JAK pathway.

The JAK program is designed to bring differentiated selectivity to a broad set of autoimmune and inflammatory disease opportunities.

Selective JAK 1/3 inhibitor

A preclinical asset designed to address inflammatory signaling through JAK 1/3 selectivity.

Selective JAK 1 inhibitor

A complementary preclinical asset focused on selective JAK 1 pathway modulation.

Two distinct assets

A dual-asset approach supports program flexibility across disease settings.

Originator expertise

The program originated with Impetis Biosciences Limited, a TATA Enterprise.

Program outlook

Building a differentiated immunology franchise.

Vyome is advancing its JAK inhibitor programs to address autoimmune disease opportunities with selective, purpose-built assets.

Autoimmune disease opportunity

Advancing

Preclinical programs in progress

View the full pipeline

A Cambridge, MA, based global healthcare platform synergizing biotech, medical devices, and AI.

Vyome Holdings, Inc.
Nasdaq: HIND

PRINCIPAL OFFICE

Harvard Square, One Mifflin Place, Suite 400, Cambridge, MA 02138

PHONE

+1 973-832-8147

SUBSIDIARIES

⁠Vyome Therapeutics, Inc.

OFFICE

Harvard Square, One Mifflin Place, Suite 400, Cambridge, MA 02138

Vyome Therapeutics Limited, Subsidiary of Vyome Therapeutics, Inc.

OFFICE

Plot No. 465, Ground Floor, F.I.E., Patparganj Industrial Area, Delhi, India- 110092.

PHONE

+91-99682-17333

*Certain statements on this site are forward-looking within the meaning of federal securities laws. Please see our full disclaimer here.

Vyome Holdings, Inc.
Nasdaq: HIND

PRINCIPAL OFFICE

Harvard Square, One Mifflin Place, Suite 400, Cambridge, MA 02138

PHONE

+1 973-832-8147

SUBSIDIARIES

⁠Vyome Therapeutics, Inc.

OFFICE

Harvard Square, One Mifflin Place, Suite 400, Cambridge, MA 02138

Vyome Therapeutics Limited, Subsidiary of Vyome Therapeutics, Inc.

OFFICE

Plot No. 465, Ground Floor, F.I.E., Patparganj Industrial Area, Delhi, India- 110092.

PHONE

+91-99682-17333

*Certain statements on this site are forward-looking within the meaning of federal securities laws. Please see our full disclaimer here.

A Cambridge, MA, based global healthcare platform synergizing biotech, medical devices, and AI.

Vyome Holdings, Inc.
Nasdaq: HIND

PRINCIPAL OFFICE

Harvard Square, One Mifflin Place, Suite 400, Cambridge, MA 02138

PHONE

+1 973-832-8147

SUBSIDIARIES

⁠Vyome Therapeutics, Inc.

OFFICE

Harvard Square, One Mifflin Place, Suite 400, Cambridge, MA 02138

Vyome Therapeutics Limited, Subsidiary of Vyome Therapeutics, Inc.

OFFICE

Plot No. 465, Ground Floor, F.I.E., Patparganj Industrial Area, Delhi, India- 110092.

PHONE

+91-99682-17333

*Certain statements on this site are forward-looking within the meaning of federal securities laws. Please see our full disclaimer here.